| dc.contributor.author | Espitia de la Hoz, Franklin | spa |
| dc.date.accessioned | 2024-04-15T00:00:00Z | |
| dc.date.available | 2024-04-15T00:00:00Z | |
| dc.date.issued | 2024-04-15 | |
| dc.description.abstract | Introducción: a pesar de los múltiples tratamientos para la vaginosis bacteriana, más de la mitad de las mujeres experimentan recurrencia de los síntomas. Objetivo: evaluar la efectividad y seguridad de las intervenciones terapéuticas en el manejo de la vaginosis bacteriana recurrente, en mujeres no gestantes. Métodos: se realizó una búsqueda sistemática de la literatura en diferentes bases de datos electrónicas (MEDLINE, Scopus, Embase, Biblioteca Cochrane, entre otras); entre 1990 y 2023. Se utilizaron términos de búsqueda libres y estandarizados. Los desenlaces evaluados fueron el tiempo de retardo en la aparición de VB mayor a 12 meses y las reacciones adversas. Resultados: se tuvieron en cuenta 84 publicaciones. El metronidazol y la clindamicina siguen siendo el régimen terapéutico recomendado en el tratamiento de la vaginosis bacteriana aguda, y en la recurrente; el secnidazol y nifuratel han mostrado su positivo efecto, escalonando una posición entre estos regímenes (los cuales no solo podrían aumentar las tasas de curación clínica y microbiológica, sino disminución en la recurrencia). La proporción de reacciones adversas fueron más notables con los nitroimidazoles y la clindamicina, sin hallarse reportes del nifuratel. Conclusión: la revisión mostró que en el tratamiento de la vaginosis bacteriana recurrente no se observan diferencias significativas entre los regímenes tradicionales, lo mismo sucede con la seguridad, ya que las reacciones adversas son escasas y no suelen ser graves. Se necesitan ensayos clínicos que ayuden a aumentar las opciones de tratamiento para la VB recurrente, dándole paso al nifuratel y a otras opciones terapéuticas. | spa |
| dc.description.abstract | Introduction: despite multiple treatments for bacterial vaginosis (BV), more than half of women experience recurrence of symptoms. Objective: to evaluate the effectiveness and safety of therapeutic interventions in the management of recurrent bacterial vaginosis in non-pregnant women. Methods: a systematic literature search was carried out in different electronic databases (MEDLINE, Scopus, Embase, Cochrane Library, among others); between 1990 and 2022. Free and standardized search terms were used. The outcomes evaluated were the delay time in the appearance of BV greater than 12 months and the adverse reactions. Results: eighty-four publications were included. Metronidazole and clindamycin continue to be the recommended therapeutic regimen in the treatment of acute bacterial vaginosis, and in recurrent one; secnidazole and nifuratel have shown their positive effect, staggering one position between these regimens (which could not only increase clinical and microbiological cure rates, but also decrease recurrence). The proportion of adverse reactions were more notable with nitroimidazoles and clindamycin, without finding reports of nifuratel. Conclusions: the review showed that in the treatment of recurrent bacterial vaginosis there are no significant differences between traditional regimens, the same happens with safety, since adverse reactions are rare and not usually serious. Clinical trials are needed to help increase treatment options for recurrent BV, making way for nifuratel and other treatment options. | eng |
| dc.format.mimetype | application/pdf | spa |
| dc.identifier.doi | 10.32997/rcb-2024-4239 | |
| dc.identifier.eissn | 2389-7252 | |
| dc.identifier.issn | 2215-7840 | |
| dc.identifier.url | https://doi.org/10.32997/rcb-2024-4239 | |
| dc.language.iso | spa | spa |
| dc.publisher | Universidad de Cartagena | spa |
| dc.relation.bitstream | https://revistas.unicartagena.edu.co/index.php/cbiomedicas/article/download/4239/3821 | |
| dc.relation.citationendpage | 79 | |
| dc.relation.citationissue | 2 | spa |
| dc.relation.citationstartpage | 65 | |
| dc.relation.citationvolume | 13 | spa |
| dc.relation.ispartofjournal | Revista Ciencias Biomédicas | spa |
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| dc.relation.references | Johnson SR, Griffiths H, Humberstone FJ. Attitudes and experience of women to common vaginal infections. J Low Genit Tract Dis. 2010;14(4):287-94. doi: 10.1097/LGT.0b013e3181d85bb7. | spa |
| dc.rights | Franklin Espitia de la Hoz - 2024 | spa |
| dc.rights.accessrights | info:eu-repo/semantics/openAccess | spa |
| dc.rights.coar | http://purl.org/coar/access_right/c_abf2 | spa |
| dc.rights.creativecommons | Esta obra está bajo una licencia internacional Creative Commons Atribución-NoComercial-SinDerivadas 4.0. | spa |
| dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/4.0 | spa |
| dc.source | https://revistas.unicartagena.edu.co/index.php/cbiomedicas/article/view/4239 | spa |
| dc.subject | Vaginosis | eng |
| dc.subject | Bacterial | eng |
| dc.subject | Therapeutics | eng |
| dc.subject | Leukorrhea | eng |
| dc.subject | Anti-Bacterial Agents | eng |
| dc.subject | Gardnerella vaginalis | eng |
| dc.subject | Vaginosis Bacteriana | spa |
| dc.subject | Terapéutica | spa |
| dc.subject | Leucorrea | spa |
| dc.subject | Antibacterianos | spa |
| dc.subject | Gardnerella vaginalis | spa |
| dc.title | Tratamiento de la Vaginosis Bacteriana recurrente, actualización 2023 | spa |
| dc.title.translated | Treatment of recurrent Bacterial Vaginosis, update 2023 | eng |
| dc.type | Artículo de revista | spa |
| dc.type.coar | http://purl.org/coar/resource_type/c_6501 | spa |
| dc.type.coar | http://purl.org/coar/resource_type/c_dcae04bc | spa |
| dc.type.coarversion | http://purl.org/coar/version/c_970fb48d4fbd8a85 | spa |
| dc.type.content | Text | spa |
| dc.type.driver | info:eu-repo/semantics/article | spa |
| dc.type.local | Journal article | eng |
| dc.type.redcol | http://purl.org/redcol/resource_type/ARTREV | spa |
| dc.type.version | info:eu-repo/semantics/publishedVersion | spa |
| dspace.entity.type | Publication | spa |
Sede: Claustro de San Agustín, Centro Histórico, Calle de la Universidad Cra. 6 #36-100
Colombia, Bolívar, Cartagena
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