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Sede: Claustro de San Agustín, Centro Histórico, Calle de la Universidad Cra. 6 #36-100
Colombia, Bolívar, Cartagena
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dc.contributor.author | Pájaro, Nehomar | spa |
dc.contributor.author | Hernández-Beltrán, Natalia | spa |
dc.contributor.author | Flórez, Mónica | spa |
dc.contributor.author | Rico-Fontalvo, Jorge | spa |
dc.contributor.author | Daza-Arnedo , Rodrigo | spa |
dc.contributor.author | Leal-Martínez, Víctor | spa |
dc.contributor.author | Sánchez-Álvarez, Christian | spa |
dc.contributor.author | Bello-Espinosa, Ariel | spa |
dc.contributor.author | Raad-Sarabia, Maria | spa |
dc.date.accessioned | 2022-10-15 00:00:00 | |
dc.date.available | 2022-10-15 00:00:00 | |
dc.date.issued | 2022-10-15 | |
dc.description.abstract | Introducción: la infección generada por el nuevo coronavirus SARS-CoV-2 ha mostrado un aumento creciente en los últimos meses, presentando manifestaciones clínicas variadas desde síntomas leves hasta afectación pulmonar grave. Además, se han descrito formas clínicas atípicas, en las que predominan los síntomas extrapulmonares; entre ellas, se han notificado casos de manifestaciones neurológicas concurrentes. A partir de la identificación de coronavirus en el sistema nervioso central en el brote de SARS-CoV de 2020, se ha planteado un posible neurotropismo del SARS-CoV-2. En la literatura mundial se han descrito pocos pacientes con encefalitis aguda, eventos cerebrovasculares isquémicos y afectación de la médula espinal asociados al SARS-CoV-2. Caso clínico: varón de 57 años, con antecedentes de hipertensión controlada, acude al servicio de urgencias con ocho días de tos no productiva, asociada a un aumento subjetivo de la temperatura corporal. La exploración física al ingreso reveló taquipnea, fiebre de 38 °C, tensión arterial y frecuencia cardiaca normales; se realiza una radiografía de tórax que muestra neumonía grave, posteriormente evolucionó a insuficiencia ventilatoria que requirió manejo en unidad de cuidados intensivos para soporte con ventilación mecánica no invasiva. Infección por SARS-CoV confirmada con RT-PCR. Conclusión: en este reporte presentamos un paciente con mielitis transversal concurrente a COVID-19, revisamos la literatura y discutimos los hallazgos clínicos e imagen dados por la enfermedad. | spa |
dc.description.abstract | Introduction: the infection generated by the new SARS-CoV-2 coronavirus has shown a growing increase in recent months, showing varied clinical manifestations, from mild symptoms to severe pulmonary involvement. In addition, atypical clinical forms have been described, in which extrapulmonary symptoms predominate; among them, cases of concurrent neurological manifestations have been reported. Based on the identification of coronavirus in the central nervous system in the 2020 SARS-CoV outbreak, a potential neurotropism of SARS-CoV-2 has been raised. Few patients with acute encephalitis, ischemic cerebrovascular events and spinal cord involvement associated with SARS-CoV-2 have been described in the world literature. Clinic case: 57-year-old man with a history of controlled hypertension, presented to the emergency department with eight days of non-productive cough, associated with a subjective increase in body temperature. Physical examination on admission revealed tachypnea, fever of 38 °C, normal blood pressure and heart rate; a chest x-ray was performed that shows severe pneumonia, and later he progressed to ventilatory failure that required intensive care unit management for support with noninvasive mechanical ventilation. SARS-CoV2 infection confirmed with RT-PCR. Conclusions: in this report we present a patient with transverse myelitis concurrent to Covid-19, we review the literature and discuss the clinical and imaging findings given by the disease. | eng |
dc.format.mimetype | application/pdf | spa |
dc.identifier.doi | 10.32997/rcb-2022-3734 | |
dc.identifier.eissn | 2389-7252 | |
dc.identifier.issn | 2215-7840 | |
dc.identifier.url | https://doi.org/10.32997/rcb-2022-3734 | |
dc.language.iso | spa | spa |
dc.publisher | Universidad de Cartagena | spa |
dc.relation.bitstream | https://revistas.unicartagena.edu.co/index.php/cbiomedicas/article/download/3734/3407 | |
dc.relation.citationedition | Núm. 4 , Año 2022 | spa |
dc.relation.citationendpage | 290 | |
dc.relation.citationissue | 4 | spa |
dc.relation.citationstartpage | 286 | |
dc.relation.citationvolume | 11 | spa |
dc.relation.ispartofjournal | Revista Ciencias Biomédicas | spa |
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dc.relation.references | Ahmad I, Rathore FA. Neurological manifestations and complications of COVID-19: A literature review. Journal of Clinical Neuroscience. 2020; 17(2): 181-92. https://doi:10.1016/j.jocn.2020.05.017 | spa |
dc.relation.references | Pfefferkorn T, Dabitz R, von Wernitz-Keibel T, Aufenanger J, Nowak-Machen M, Janssen H. Acute polyradiculoneuritis with locked-in syndrome in a patient with Covid-19. Journal of Neurology. 2020. https://doi:10.1007/s00415-020-09897-y | spa |
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dc.relation.references | Berth SH, Leopold PL, Morfini GN. Virus-induced neuronal dysfunction and degeneration. Front. Biosci. (Landmark Ed) 2009; 14(14), 5239–5259. https://doi.org/10.2741/3595 | spa |
dc.relation.references | Mao L, Wang M, Chen Sh, He Q, Chang J, Hong C, et al. Neurological Manifestations of Hospitalized Patients with COVID-19 in Wuhan, China: A Retrospective Case Series Study (February 24, 2020). https://doi:10.1001/jamaneurol.2020.1127 | spa |
dc.relation.references | Sotoca J, Rodriguez-Alvarez. COVID-19-associated acute necrotizing myelitis. Neurol Neuroimmunol Neuroin amm 7:e803. https://doi.org/10.1212/NXI.0000000000000803 | spa |
dc.relation.references | Poyiadji N, Shahin G, Noujaim D, Stone M, Patel S. COVID-19-associated acute hemorrhagic necrotizing encepha- lopathy CT and MRI features. Radiology. 2020; 6:97–123. doi:10.1148/radiol.2020201187 | spa |
dc.relation.references | Toscano G, Palmerini F, Ravaglia S et al. Guillain-Barré syndrome associated with SARS-CoV-2. N Engl J Med. 2020; 4:9 https://doi:10.1056/NEJMc2009191 | spa |
dc.relation.references | Gutiérrez-Ortiz C, Méndez A, Rodrigo-Rey S et al Miller Fisher syndrome and polyneuritis cranialis in COVID-19. Neurology. 2020; 7:16. | spa |
dc.relation.references | Kang Zhao, Jucun Huang, Dan Dai, Yuwei Feng, Liming Liu, ShukeNiemedRxivAcute myelitis after SARS-CoV-2 infection: a case report. 2020; doi: https://doi.org/10.1101/2020.03.16.2003510 | spa |
dc.relation.references | Sarma, D., & Bilello, L. A. A Case Report of Acute Transverse Myelitis Following Novel Coronavirus Infection. Clinical Practice and Cases in Emergency Medicine. 2020; 17(2): 181-92. https://doi:10.5811/cpcem.2020.5.47937 | spa |
dc.relation.references | Maideniuc C, Memon A. Acute necrotizing myelitis and acute motor axonal neuropathy in a COVID‐19 patient. Journal of Neurology. 2020; 17(2): 181-92. https://doi:10.1007/s00415-020-10145-6 | spa |
dc.relation.references | Scotti G, Gerevini S. Diagnosis and differential diagnosis of acute transverse myelopathy. The role of neuroradiological investigations and review of the literature. 2020; 17(2): 181-92. https://doi:10.1007/s100720100038 | spa |
dc.rights | Nehomar Pájaro - 2023 | spa |
dc.rights.accessrights | info:eu-repo/semantics/openAccess | spa |
dc.rights.coar | http://purl.org/coar/access_right/c_abf2 | spa |
dc.rights.creativecommons | Esta obra está bajo una licencia internacional Creative Commons Atribución-NoComercial-SinDerivadas 4.0. | spa |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/4.0 | spa |
dc.source | https://revistas.unicartagena.edu.co/index.php/cbiomedicas/article/view/3734 | spa |
dc.subject | Covid-19 | eng |
dc.subject | Transverse myelitis | eng |
dc.subject | Plasmapheresis | eng |
dc.subject | Covid-19 | spa |
dc.subject | Mielitis transversa | spa |
dc.subject | Plasmaféresis | spa |
dc.title | Mielitis aguda como manifestación de infección por sars-cov-2 | spa |
dc.title.translated | Acute myelitis as a manifestation of SARS-CoV-2 infection | eng |
dc.type | Artículo de revista | spa |
dc.type.coar | http://purl.org/coar/resource_type/c_6501 | spa |
dc.type.coar | http://purl.org/coar/resource_type/c_6501 | spa |
dc.type.coarversion | http://purl.org/coar/version/c_970fb48d4fbd8a85 | spa |
dc.type.content | Text | spa |
dc.type.driver | info:eu-repo/semantics/article | spa |
dc.type.local | Journal article | eng |
dc.type.redcol | http://purl.org/redcol/resource_type/ARTREF | spa |
dc.type.version | info:eu-repo/semantics/publishedVersion | spa |
dspace.entity.type | Publication |
Sede: Claustro de San Agustín, Centro Histórico, Calle de la Universidad Cra. 6 #36-100
Colombia, Bolívar, Cartagena
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