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dc.contributor.authorMaldonado Rojas, Wilson
dc.date.accessioned2017-06-01T19:57:35Z
dc.date.available2017-06-01T19:57:35Z
dc.date.issued2016
dc.identifier.citationTD542.1 / M293es
dc.identifier.urihttp://hdl.handle.net/11227/4567
dc.descriptionThesis (Doctor in Environmental Toxicology). -- University cartagena. Faculty of Pharmaceutical Sciences. Environmental Toxicology Program, 2016es
dc.description.abstractIn this thesis are presented the results of a multidisciplinary methodological strategy that included powerful computational tools such as molecular docking (AutoDock vina, GOLD and Surflex-Dock, SYBYL), pharmocophoremapping (Ligand Scout 3.0) combined with statistical methods (cluster analisis, lincar discriminant analysis, linear regression, among others) to the search for natural compounds with anticancer activity by inhibition of cancer targets such as, COX-2, iNos and DNMT1.es
dc.format.mediumapplication/pdf
dc.language.isoenges
dc.publisherUniversity cartagenaes
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0
dc.subjectPruebas de toxicidad in vitroes
dc.subjectCompuestos orgánicos - Investigacioneses
dc.subjectBlancos moleculareses
dc.subjectCáncer - Inhibidores de proteasaes
dc.titleNatural bioactive compounds as inhibitors of cáncer targetses
dc.typeinfo:eu-repo/semantics/doctoralThesis
dc.typedoctoralThesises
dc.rights.accessopenAccess


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