Endocrine disruptors as ligands of breast cancer proteins
Trabajo de grado - Doctorado
2015
Universidad de Cartagena
Thesis was to evaluate the plausibility of EDCs to bind breast cancer proteins, through a three-steps approach: creation of a database of EDCs with three-dimensional structure available, an inverse virtual screening of bisphenol A (BPA) -one of the xenoestrogens to which we are most frequently exposed to- against proteins involved in different signaling pathways, and a virtual high-throughput screening (vHTS) among EDCs and proteins involved in this disease with an evaluation of the interactions of a protein-ligand complex through spectroscopic methods.
Tesis (Doctor en Toxicología Ambiental) - Universidad de Cartagena, Facultad de Ciencias Farmacéuticas. Programa de Toxicología Ambiental, 2015
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Thesis_DianaMontes_2015.pdf
Título: Thesis_DianaMontes_2015.pdf
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Título: Thesis_DianaMontes_2015.pdf
Tamaño: 6.952Mb
PDFLEER EN FLIP