dc.contributor.author | Dueñas-Castell, Carmelo | spa |
dc.contributor.author | Coronell, Wilfrido | spa |
dc.contributor.author | Borré-Naranjo, Diana | spa |
dc.contributor.author | Almanza, Amilkar | spa |
dc.contributor.author | Lora Lián, Leydis | spa |
dc.contributor.author | Navarro, Rafael | spa |
dc.contributor.author | Rojas-Suarez, Jose | spa |
dc.date.accessioned | 2022-04-15 00:00:00 | |
dc.date.available | 2022-04-15 00:00:00 | |
dc.date.issued | 2022-04-15 | |
dc.identifier.issn | 2215-7840 | |
dc.description.abstract | Introducción: hasta la fecha, pocos estudios informaron variaciones máximas en la infección por COVID-19 en países de ingresos bajos y medios. Nuestro objetivo fue explorar las posibles razones de los cambios epidemiológicos con el tiempo. Métodos: este estudio se realizó en un centro de referencia de tercer nivel en Cartagena, Colombia, entre el 7 de marzo de 2020 y el 28 de febrero de 2021. Se incluyeron pacientes adultos con sospecha o confirmación de COVID-19. Categorizamos el período de estudio en dos según los picos definidos en Colombia: el primer período abarcó las semanas epidemiológicas 10-35 (7 de marzo al 30 de agosto de 2020) y el segundo período abarcó las semanas 36 a 60 (1 de septiembre de 2020 - 28 de febrero de 2021). Ajustamos la mortalidad por covariables para identificar posibles cambios. Resultados: en total, 2761 pacientes con COVID-19 fueron hospitalizados. Comparando los dos períodos, el número de casos fue mayor durante la semana 21 (pico 1: 121 pacientes) y la semana 50 (pico 2: 128 pacientes), respectivamente. La tasa de mortalidad disminuyó del 16,5 % (IC del 95 %: 13,3 a 19,8) en la semana 10 al 8,91 (IC del 95 %: 6,95 a 10,8) en la semana 60 (valor de p <0,001). Conclusión: nuestro estudio es el primero en informar un seguimiento de un año durante la pandemia de CO-VID-19 en un país de ingresos bajos y medios. Encontramos una menor tasa de mortalidad durante el segundo período, posiblemente explicada por un aumento en la experiencia y una mejor organización con los recursos de salud.  | spa |
dc.description.abstract | Introduction: to date, few studies reported peak variations in COVID-19 infection in low-and middle-income countries. We aimed to explore the potential reasons for epidemiological changes with time. Methods: this study was conducted at a tertiary referral center in Cartagena, Colombia, between March 7, 2020 and February 28, 2021. Were included adult patients with suspected or confirmed COVID-19. We categorized the study period into two according to the peaks defined in Colombia: the first period included epidemiological weeks 10-35 (March 7, 2020 - August 30, 2020), and the second period included weeks 36-60 (September 1, 2020 - February 28, 2021). We adjusted the mortality by covariates to identify potential changes. Results: in total, 2761 COVID-19 patients were hospitalized. Comparing the two periods, the number of cases was higher during week 21 (peak1: 121 patients) and week 50 (peak2: 128 patients), respectively. The mortality rate declined from 16.5% (95% CI 13.3-19.8) in week 10 to 8.91 (CI 95% 6.95-10.8) in week 60 (p-value <0.001). Conclusions: our study is the first to report a one-year follow-up during the COVID-19 pandemic in a low-and middle-income country. We found a lower mortality rate during the second period, possibly explained by an increase in the experience and a better organization with health resources.  | eng |
dc.format.mimetype | application/pdf | eng |
dc.language.iso | eng | eng |
dc.publisher | Universidad de Cartagena | spa |
dc.relation.ispartofjournal | Revista Ciencias Biomédicas | spa |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-sa/4.0 | eng |
dc.source | https://revistas.unicartagena.edu.co/index.php/cbiomedicas/article/view/3932 | eng |
dc.subject | COVID-19 | eng |
dc.subject | Reverse Transcriptase Polymerase Chain Reaction | eng |
dc.subject | patient admission | eng |
dc.subject | pandemics | eng |
dc.subject | COVID-19 | spa |
dc.subject | Reacción en cadena de la polimerasa con transcriptasa inversa | spa |
dc.subject | admisión de pacientes | spa |
dc.subject | pandemias | spa |
dc.title | Variaciones hospitalarias durante el primer año de la pandemia de COVID-19 en un hospital de referencia en un país de ingresos bajos a medios: un gran estudio de cohorte de un solo centro | spa |
dc.type | Artículo de revista | spa |
dc.title.translated | Hospital variations during the first year of the COVID-19 pandemic in a referral hospital in a low-to-middle-income country: a large single-center cohort study | eng |
dc.identifier.doi | 10.32997/rcb-2022-3932 | |
dc.type.version | info:eu-repo/semantics/publishedVersion | eng |
dc.type.coarversion | http://purl.org/coar/version/c_970fb48d4fbd8a85 | eng |
dc.rights.coar | http://purl.org/coar/access_right/c_abf2 | eng |
dc.identifier.eissn | 2389-7252 | |
dc.identifier.url | https://doi.org/10.32997/rcb-2022-3932 | |
dc.relation.bitstream | https://revistas.unicartagena.edu.co/index.php/cbiomedicas/article/download/3932/3197 | |
dc.relation.citationedition | Núm. 2 , Año 2022 | spa |
dc.relation.citationendpage | 114 | |
dc.relation.citationissue | 2 | spa |
dc.relation.citationstartpage | 103 | |
dc.relation.citationvolume | 11 | spa |
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dc.rights.accessrights | info:eu-repo/semantics/openAccess | eng |
dc.rights.creativecommons | Esta obra está bajo una licencia internacional Creative Commons Atribución-NoComercial-CompartirIgual 4.0. | eng |
dc.type.coar | http://purl.org/coar/resource_type/c_6501 | eng |
dc.type.coar | http://purl.org/coar/resource_type/c_2df8fbb1 | eng |
dc.type.content | Text | eng |
dc.type.driver | info:eu-repo/semantics/article | eng |
dc.type.local | Journal article | eng |
dc.type.redcol | http://purl.org/redcol/resource_type/ART | eng |