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Modelado molecular de análogos estructurales de las Acil homoserina lactonas en el sitio activo del receptor Lasr

dc.contributor.advisorVivas Reyes, Ricardo (Director/a)
dc.contributor.advisorAlí Torres, Jorge Isaac (Director/a)
dc.contributor.advisorZapata Rivera, Jhon (Director/a)
dc.contributor.authorAhumedo Monterrosa, Maicol José
dc.date.accessioned2020-03-13T14:22:00Z
dc.date.available2020-03-13T14:22:00Z
dc.date.issued2018
dc.identifier.citationTD541.28 / A86es
dc.identifier.urihttps://hdl.handle.net/11227/10030
dc.identifier.urihttp://dx.doi.org/10.57799/11227/79
dc.descriptionTesis (Doctor en Ciencias). -- Universidad de Cartagena. Facultad de Ciencias Exactas y Naturales, 2018es
dc.description.abstractEn el presente trabajo, se realizó un estudio de modelado molecular que combina cálculos de acoplamiento molecular, relación cuantitativa estructura actividad 3D basado en el receptor, simulaciones de dinámica molecular y cálculos de energía libre de unión, sobre un conjunto de 28 análogos estructurales de las N-acil homoserina lactonas (AHLs) con actividad antagonista de Quorum sensing, con el propósito de comprender el modo de unión y el microambiente molecular al cual están expuestos los 28 análogos en el sitio activo del receptor LasR en Pseudomona aeruginosaes
dc.format.mediumapplication/pdf
dc.language.isospaes
dc.publisherUniversidad de Cartagenaes
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/4.0
dc.subjectEstructura moleculares
dc.subjectQuímica cuánticaes
dc.subjectQuímicaes
dc.titleModelado molecular de análogos estructurales de las Acil homoserina lactonas en el sitio activo del receptor Lasres
dc.typeTrabajo de grado - Doctoradospa
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