Endocrine disruptors as ligands of breast cancer proteins

Montes G., Diana

dc.contributor.author	Montes G., Diana
dc.date.accessioned	2017-03-23T19:03:03Z
dc.date.available	2017-03-23T19:03:03Z
dc.date.issued	2015
dc.identifier.citation	TD616.99249 / M764	es
dc.identifier.uri	https://hdl.handle.net/11227/4259
dc.identifier.uri	http://dx.doi.org/10.57799/11227/153
dc.description	Tesis (Doctor en Toxicología Ambiental) - Universidad de Cartagena, Facultad de Ciencias Farmacéuticas. Programa de Toxicología Ambiental, 2015	es
dc.description.abstract	Thesis was to evaluate the plausibility of EDCs to bind breast cancer proteins, through a three-steps approach: creation of a database of EDCs with three-dimensional structure available, an inverse virtual screening of bisphenol A (BPA) -one of the xenoestrogens to which we are most frequently exposed to- against proteins involved in different signaling pathways, and a virtual high-throughput screening (vHTS) among EDCs and proteins involved in this disease with an evaluation of the interactions of a protein-ligand complex through spectroscopic methods.	es
dc.format.medium	application/pdf
dc.language.iso	eng	es
dc.publisher	Universidad de Cartagena	es
dc.rights.uri	https://creativecommons.org/licenses/by-nc-nd/4.0
dc.subject	Endocrinología	es
dc.subject	Mamas - Tumores	es
dc.title	Endocrine disruptors as ligands of breast cancer proteins	es
dc.type	Trabajo de grado - Doctorado	spa
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